HOME > ENGLISH > FACULTY > CONTENT
ENGLISH
CHEN Yan

 

           Yan Chen, Ph.D.

Associate Professor, School  of Life Science, Jilin University

email: chen_yan@jlu.edu.cn

Tel:+86-0431-85167795

Fax:+86-0431-85167751

Life Science Building, Jilin University, Qianjin Street No.2699,Changchun,P. R. China,

Postal Code:130012

Scientific research field description

The delivery system of biomacromolecule, including new delivery carriers of protein and peptide drug, non-viral vectors of gene therapy, adjuvants of DNA and protein vaccine.

Representative papers

 

[1]. Wang Mengshu, Zhang Yong, Feng Jiao, Gu Tiejun, Dong Qingguang, Yang Xu, Sun Yanan, Wu Yongge, Chen Yan*, Kong Wei*. Preparation, characterization and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4. International Journal of Nanomedicine, 2013, 8:1141-1154.

[2]. Qing-Guang Dong, Yong Zhang, Meng-Shu Wan, Jiao Feng, Hai-Hong Zhang, Yong-Ge Wu, Tie-Jun Gu, Xiang-Hui Yu, Chun-Lai Jiang, Yan Chen*,Wei Li, Wei Kong. Improvement of enzymatic stability and intestinal permeability of deuterohemin-peptide conjugates by specific multi-site N-methylation. Amino Acids ,2012, 43:2431-2441.

[3] .Wang MS, Sun BX, Feng J, Zhang HH, Liu B, Li C, Chen Y*, Zhang Y*, Kong W. Investigation of transport mechanism of exendin-4 across MDCK cell monolayers. Biol. Pharm. Bull. 2012, 35(5) 745-752.

[4] .Bin Liu, Qingguang Dong, Mengshu Wang, Lin Shi, Yongge Wu, Xianghui Yu, Yanyu Shi, Yaming Shan, Chunlai Jiang, Xizhen Zhang, Tiejun Gu, Yan Chen*, Wei Kong*. Preparation, Characterization, and Pharmacodynamics of Exenatide-Loaded Poly(DL-lactic-co-glycolic acid) Microspheres. Chem. Pharm. Bull., 2010, 58(11): 1474-1479.

[5]. Bin Liu, Qingguang Dong, Lin Shi, Mengshu Wang, Chun Li, Yongge Wu, Xianghui Yu, Yaming Shan, Yan Chen*, Wei Kong*, Jiacong Shen. Development and Validation of a Reverse-phase High Performance Liquid Chromatography Method for Determination of Exenatide in Poly(lactic-co-glycolic acid) Microspheres. Chemical Research in Chinese Universities, 2010, 26(1), 33-37.

 

College of Life Sciences, Jilin University,Changchun,China,130012

Tel:+86-431-81969061  Email: smxyld@jlu.edu.cn