师资队伍

细胞生物学与生物物理学系

杨方

日期:2020-08-11 点击数: 来源:

   名:

杨方

 

      称:

教授

最高学位:

博士研究生

   话:

15543008253

   件:

fangyang@jlu.edu.cn

工作地点:

生科楼237

研究方向

基于微流控系统的新型生物检测和分析技术:(1)微流控液体活检技术;(2)细胞分选、分析技术;(3)微流控快速混合传质技术;(4)微流控微纳材料合成技术。

教育经历

2008.7 - 2013.5 美国南卡罗莱纳大学,获博士学位

2005.9 - 2008.5 吉林大学,获理学硕士学位

2001.9 - 2005.7 吉林大学,获理学学士学位

工作经历

2023.9 - 至今 吉林大学分子酶学工程教育部重点实验室,教授

2016.6 - 2023.9 吉林大学分子酶学工程教育部重点实验室,副教授

2014.2 - 2016.2 美国卡内基梅隆大学生物医学工程系, 博士后

2013.5 - 2014.2 美国南卡罗莱纳大学,机械工程与生物医学工程交叉项目,博士后

荣誉称号

吉林大学海外博士A类引进人才

 

 

研究成果

科研项目:

国家自然科学基金青年基金 2018/012020/12,项目负责人

中国博士后科学基金面上项目2017/012019/12, 项目负责人

吉林省科技厅自然科学基金项目2019/01 ~ 2021/12,项目负责人

吉林省发改委产业技术研究与开发专项项目2019/01 ~2020/12,项目负责人

吉林省科技厅优秀青年人才基金项目 2017/01 ~ 2018/12, 项目负责人

吉林大学“学科交叉融合创新”项目 2021.01-2022.12 项目负责人

吉林大学青年师生交叉学科项目 2017/04 ~ 2019/04, 项目负责人

吉林大学海外博士A类人才科研启动基金 2016 ~ 2018, 项目负责人

 

国家发明专利:

1. 一种内置透明电极的全透明微流控芯片及其制备方法 ZL201710644638.2 已授权

2. 一种实现全血血浆持续分离的微流控器件及其分离方法 ZL201710644637.8 已授权

3.  一种实现低电压电致细胞裂解的微流控器件及其裂解细胞的方法,ZL201710789161.7 已授权

 

发表SCI文章:

 

1. Jianqiu Zhao, Na Li, Xinyu Zhou, Zihan Yu, Mei Lan, Siyu Chen, Jiajia Miao, Yulai Li, Guiying Li and Fang Yang *, Electrolysis of Bacteria Based on Microfluidic Technology, Micromachines, 2023, 14(1), 144

2. Na Li, Yu Jiang, Tianyi Lv, Guiying Li*, FangYang*, Immunofluorescence analysis of breast cancer biomarkers using antibody-conjugated microbeads embedded in a microfluidic-based liquid biopsy chip, Biosensors and Bioelectronics, 2022, 216, 114598

3. Mingzhan Liu, Na Li, Shunyu Cui, Guiying Li*, and Fang Yang*, Biochemical Reaction Acceleration by Electrokinetic Mixing in a Microfluidic Chip, The Journal of Physical Chemistry Letters, 2022, 13(24), 5633-5637

4. Fang Yang, Wei Zhao, and Guiren Wang*, Electrokinetic mixing of two fluids with equivalent conductivity, Chinese Journal of Chemical Engineering, 2022, 42, 256-260

5. Fang Yang*, Wei Zhao, Cuifang Kuang, and Guiren Wang*. Rapid AC Electrokinetic Micromixer with Electrically Conductive Sidewalls, Micromachines, 2022, 13(1), 34. https://doi.org/10.3390/mi13010034

6. Jialiang Zhao, Jingjing Xu, Tianbin Yang, Xinze Yu, Cheng Cheng, Tong Zhang, Ze Ren, Na Li, Fang Yang*, Guiying Li*, Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody. BMC Biotechnology, 2021, 21, 71. https://doi.org/10.1186/s12896-021-00729-z

7. Guiying Li, Weiwei Tang, Fang Yang*Cancer Liquid Biopsy Using Integrated Microfluidic Exosome Analysis Platforms, Biotechnology Journal, 2020, 15(5): 1900225. https://doi.org/10.1002/biot.201900225 

8. Ying Zhang, Shangyu Wang, Jie Chen, Fang Yang*, Guiying Li*, Separation of Macrophages Using a Dielectrophoresis-Based Microfluidic Device, BioChip Journal, 2020, 14, 185–194

9. Xiaoyu Wei, Jinhua Li, Lei Wang, Fang Yang*, Low-Voltage Electrical Cell Lysis Using a Microfluidic Device, Biomedical Microdevices, 2019, 21(1), 1-9

10. Fang Yang, Ying Zhang, Xi Cui, Yutong Fan, Ying Xue, Haipeng Miao, Guiying Li*, Extraction of Cell-Free Whole Blood Plasma Using a Dielectrophoresis-Based Microfluidic Device, Biotechnology Journal, 2019,14(3) 1800181

11. Fang Yang, Xiangzhi Liao, Yuan Tian, Guiying Li*, Exosome separation using microfluidic systems: size-based, immunoaffinity-based and dynamic methodologies, Biotechnology Journal, 2017, 12(4), 1600699

12. Fang Yang, Cuifang Kuang, Wei Zhao, Guiren Wang*, AC Electrokinetic Fast Mixing in Non-Parallel Microchannels, Chemical Engineering Communications, 2017, 204(2), 190-197.

13. Zhao, WeiYang, Fang (共同一作)Wang, KaigeBai, JintaoWang, Guiren*Rapid mixing by turbulent-like electrokinetic microflow, Chemical Engineering Science, 2017, 165, 113-121

14. Guiren Wang*(导师), Fang Yang, Wei Zhao, On micro-electrokinetic scalar turbulence in microfluidics at a low Reynolds number, Lab on a Chip, 2016,16, 1030-1038

15. Guiren Wang*(导师), Fang Yang, Wei Zhao, Micro-electrokinetic turbulence in microfluidics at low Reynolds number, Physics Review E, 2016, 93, 013106 

16. Fang Yang, Robert L. Kormos, James F. Antaki*, High-speed visualization of disturbed pathlines in axial flow blood pump under pulsatile conditions, The Journal of Thoracic and Cardiovascular Surgery, 2015, 150(4), 938-944

17. Guiren Wang*(导师), Fang Yang, Wei Zhao, There can be turbulence in microfluidics at low Reynolds number, Lab on a Chip, 2014, 14, 1452-1458.

18. Fang Yang, Xiaoming Yang, Hong Jiang, William M. Butler, Guiren Wang*, Dielectrophoretic Separation of Prostate Cancer Cells, Technology in Cancer Research and Treatment, 2012, 12, 61-70.

19. Fang Yang, Xiaoming Yang, Hong Jiang, Guiren Wang*, Cascade and staggered dielectrophoretic cell sorters, Electrophoresis, 2011, 32, 2377–2384.

20. Fang Yang, Xiaoming Yang, Hong Jiang, Phillip Bulkhaults, Patricia Wood, William Hrushesky, Guiren Wang*, Dielectrophoretic Separation of Colorectal Cancer Cells. Biomicrofluidics, 2010, 4, 013204 (引用数:92) 

21. Wei Zhao, Xin Liu, Fang Yang, Kaige Wang, Jintao Bai, Rui Qiao, and Guiren Wang. Study of oscillating electroosmotic flows with high temporal and spatial resolution, Analytical Chemistry, 2018, 90 (3), 1652–1659

22. Wei-Tao Wu, Fang Yang, Jingchun Wu, Nadine Aubry, Mehrdad Massoudi, James F. Antaki*. High fidelity computational prediction of thrombus formation in a continuous flow ventricular assist device: HeartMate II, Scientific Reports, 2016, 6, 38025

23. Wei Zhao, Fang Yang, Guiren Wang*, Measurement of Velocity Fluctuations in Microfluidics with Simultaneously Ultrahigh Spatial and Temporal Resolution. Experiments in Fluids, 2016, 57(1), 1-12

24. Wei-Tao Wu, Fang Yang, James F. Antaki*, Nadine Aubry, Mehrdad Massoudi, Study of blood flow in several benchmark micro-channels using a two-fluid approach, International Journal of Engineering Science, 2015,95, 49-59

25. Wei Zhao, Fang Yang, Guiren Wang*, Corrections on LIFPA velocity measurements in microchannel with moderate velocity fluctuations. Experiments in Fluids, 2015, 56, 39

26. Cuifang Kuang, Fang Yang, Wei Zhao, Guiren Wang*, Study of the Rise Time in Electroosmotic Flow within a Microcapillary. Analytical Chemistry, 2009, 81, 6590–6595.

27. Chen Zhang, Kaige Wang, Jintao Bai, Shuang Wang, Wei Zhao, Fang Yang, Changzhi Gu, Guiren Wang*, Nanopillar array with a lamda/11 diameter fabricated by a kind of visible CW laser direct lithography system, Nanoscale Research Letters, 2013, 8, 280

28. Mohammed Alshareef, Nicholas Metrakos, Eva Juarez-Perez, Fadi Azer, Fang Yang, Xiaoming Yang, Guiren Wang*. Separation of tumor cells with dielectrophoresis-based microfluidic chip. Biomicrofluidics, 2013, 7, 011803

29. Cuifang Kuang, Wei Zhao, Fang Yang, Guiren Wang*, Measuring flow velocity distribution in microchannels using molecular tracers. Microfluidics and nanofludiics, 2009, 7, 509-517.