YANG Yan,Ph.D.

Associate Professors, College of Life Sciences, Jilin University

Email: yyan@jlu.edu.cn



Life Science Building, Jilin University, Qianjin Street No.2699,Changchun,P. R. China,

Postal Code:130012

Research Interests


Representative papers

1. Hong Cao, Yan Yang*. Biocatalytic synthesis of poly(δ-valerolactone) using a thermophilic esterase from Archaeoglobus fulgidus as catalyst. Int. J. Mol. Sci. 2012, 13: 12232-12241.
2. Yan Yang, Quanshun Li*. Cell-debris self-immobilized thermophilic esterase: a novel biocatalyst for synthesizing aliphatic polyesters. J. Control. Release (Abstract for SIPCD) 2012, in press.
3. Yan Yang*. A novel thermohilic histone with promising gene transfection efficiency. J. Control. Release (Abstract for SIPCD) 2012, in press.
4. Yang Yu, Yan Yang*. Lipase/esterase-catalyzed synthesis of aliphatic polyesters via polycondensation: a review. Process Biochem. 2012, 47: 1027-1036.
5. Yan Yang, Quanshun Li*. Lipase/esterase-catalyzed ring-opening polymerization: a green polymer synthesis technique. Process Biochem. 2011, 46: 1900-1908.
6. Yan Yang, Quanshun Li*. Lipase-catalyzed synthesis of poly(ε-caprolactone) and its solid-state properties characterization. Biocatal. Biotransform. 2011, 16: 1201-1207.
7. Yang Y, Yeo Y*. Mannitol-Guided delivery of ciprofloxacin in artificial cystic fibrosis mucus model. Biotechnol. Bioeng. 2011, 108: 1441-1449.
8. Zhang, ML, Yang, Y*. Simultaneous Determination of Escin Ia and Its Isomer Isoescin Ia by LC-MS-MS: Application to a Pharmacokinetic Study of Escin Ia in Rats. Chromatographia, 2011, 74: 243-250.
9. Yang, Y., Yeo, Y*. Inhalable antibiotic delivery using a dry powder co-delivering recombinant deoxyribonuclease and ciprofloxacin for treatment of cystic fibrosis. Pharm. Res, 2010, 27: 151-160.
10. Yang, Y., Yeo, Y*. Development of highly porous large PLGA microparticles for pulmonary drug delivery. Biomaterials, 2009, 30: 1947-1953.
11. Yan Yang, Jingkai Gu*. Simultaneous quantitation of dexamethasone palmitate and dexamethasone in human plasma by liquid chromatography/tandem mass spectrometry. J. Chromatogr. B 2008, 862: 119-124.
12. Wang T, Ma W, Sun Y, Yang Y, Zhang W, Fawcett JP, Du H, Gu J. Ultra-sensitive assay for paclitaxel in intracellular compartments of A549 cells using liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2013, 912:93-7.
13. Basma Ibrahim, Michael Tsifansky, Yan Yang, Yoon Yeo*. Challenges and advances in development of inhalable drug formulations for cystic fibrosis lung disease. Expert Opin. Drug Del. 2011, 8: 451-466.
14. Zhang C, Cui X, Yang Y, Gao F, Sun Y, Gu Jingkai*, Fawcett JP, Yang W, Wang W, Pharmacokinetics of felbinac after intravenous administration of felbinac trometamol in rats. Xenobiotica. 2011, 41: 340-348.
15. Zhang, C., Wang, L., Yang, Y., Sun, Y., Zhang, J., Li, G., and Gu, J*. Validated LC-MS/MS method for the determination of sarpogrelate in human plasma: Application to a pharmacokinetic and bioequivalence study in Chinese volunteers. J Pharm Biomed Anal, 2010, 53(3): 546-551.
16. Liu L, Wu X, Wu D, Wang Y, Li P, Sun Y, Yang Y, Gu Jingkai*, Cui Y, A liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of escin Ia and escin Ib in human plasma: application to a pharmacokinetic study after intravenous administration. Biomed Chromatogr. 2010, 24: 1309-1315.
17. Wantong Song, Mingqiang Li, Zhaohui Tang, Quanshun Li, Yan Yang, Huaiyu Liu, Taicheng Duan, Hua Hong, Xuesi Chen*. Methoxy poly(ethylene glycol)-b-poly (L-glutamic acid) loaded cisplatin and a combination with iRGD for the treatment of non-small cell lung cancers. Macromol. Biosci. 2012, in press.
18. Qun He, Meiyun Shi, Xidong Liu, Yantong Sun, Lianghai Hu, Yan Yang, J. Paul Fawcett, Limei Zhao, Jiangkai Gu*. Determination of landiolol, an ultra-short-acting β1-receptor antagonist, in human plasma by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2012, 891-892, 7-11.
19. Li, MQ ;Song, WT ;Tang, ZH ; Lv, SX; Lin, L; Sun, H ; Li, QS; Yang, Y; Hong, H; Chen, XS Nanoscaled Poly(L-glutamic acid)/Doxorubicin-Amphiphile Complex as pH-responsive Drug Delivery System for Effective Treatment of Nonsmall Cell Lung Cancer ACS APPLIED MATERIALS & INTERFACES Volume: 5 Issue: 5 Pages: 1781-1792 Published: MAR 13 2013
20.Lei Yin, Meiyun Shi, Yantong Sun, Xiaocheng Sun, Huan Meng, J. Paul Fawcett,Yan Yang∗∗, Jingkai Gua,∗ A liquid chromatography–tandem mass spectrometric method for the simultaneous quantitation of five components of Ixeris sonchifoliain (Bge.) Hance in rat plasma and its application to a pharmacokinetic study;Journal of Chromatography B, 931 (2013) 12–16


College of Life Sciences, Jilin University,Changchun,China,130012

Tel:+86-431-81969061  Email: smxyld@jlu.edu.cn