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师资队伍
高印
基本情况
姓名: 高印
性别:
职称: 副教授
最高学历: 研究生
最高学位: 博士
Email:
详细情况
所在学科专业: Glycobiology 糖生物学
所研究方向: 细胞糖基化的生物功能以及抑制素药物的研发; 糖基化在细胞凋亡程序中的作用
讲授课程: 研究生课:蛋白质组学
教育经历: 2008.12:学士, 生物化学, 加拿大曼尼托巴大学
2013.07:博士, 生物化学, 加拿大女王大学
工作经历: 2013.07-2015.07: 博士后, 化学, 加拿大女王大学
2015.09-:副教授, 吉林大学生命科学学院
学术论文: (1)Yin Gao, Brendan Mossing, Gang Wu, Direct NMR detection of the unstable “red product” from reaction between nitroprusside and 2-mercaptosuccinic acid, Dalton Transactions, 2015, 44(47): 20338-20343.
(2)Yin Gao, Abouzar Toubaei, Xianqi Kong, Gang Wu, Solving the 170-Year-Old mystery about red-violet and blue transient intermediates in the Gmelin reaction, European Journal of Chemistry, 2015, 21: 17172-17177.
- This publication has been highlighted in C&EN News (By Stu Borman, “Nitroprusside Color Mystery Resolved” October 26, 2015).
(3)Yin Gao, Abouzar Toubaei, Xianqi Kong, Gang Wu, Acidity and hydrogen exchange dynamics of iron(II)-bound nitroxyl in aqueous solution, Angewandte Chemie International Edition, 2014, 53(43): 11547-11551.
(4)Yin Gao, Rajindra P. Aryal, Tongzhong Ju, Richard D. Cummings, Gagandeep Gahlay, Donald L. Jarvis, Khushi Matta, Jason Z. Vlahakis, Walter A. Szarek, Inka Brockhausen*, Acceptor specificities and selective inhibition of recombinant human Gal- and GlcNAc-transferases that synthesize core structures 1, 2, 3 and 4 of O-glycans, Biochimica et Biophysica Acta, 2013, 1830(8): 4274-4281.
(5)Yin Gao, Jason Z. Vlahakis, Walter Szarek, Inak Brockhausen, Selective inhibition of glycosyltransferases by bivalent imidazolium salts. Bioorganic & Medicinal Chemistry, 2013, 21(5): 1305-1311.
(6)Yin Gao, Bin Liu, Scott Strum, John S. Schutzbach, Tatyana N. Druzhinina, Natalia S. Utkina, Vladimir I. Torgov, Leonid L. Danilov, Vladimir V. Veselovsky, Jason Z. Vlahakis, Walter A. Szarek, Lei Wang, Inka Brockhausen, Biochemical characterization of WbdN, a β1,3-glucosyltransferase involved in O-antigen synthesis in enterohemorrhagic Escherichia coli O157, Glycobiology, 2012, 22(8): 1092 -1102.
(7)Yin Gao, Vishwanath Chachadi, Pi-Wan Cheng, Inka Brockhausen, Glycosylation potential of human prostate cancer cell lines. Glycoconjugate Journal, 2012, 29(7): 525-537.
(8)Yin Gao, Carmen Lazar, Walter A. Szarek, Inka Brockhausen, Specificity of β1,4-galactosyltransferase inhibition by 2-naphthyl 2-butanamido-2-deoxy-1-thio-β-D-glucopyranoside, Glycoconjugate Journal, 2010, 27(7): 673 -684.
(9)Shuo Wang, Diana Czuchry, Bin Liu, Anna N. Vinnikova, Yin Gao, Jason Z. Vlahakis, Walter A. Szarek, Lei Wang, Feng Lu, Inka Brockhausen, Characterization of two UDP-Gal: GalNAc-Diphosphate-lipid β1,3-Galactosyltransferases Wbwc from Escherichia coli serotypes O104 and O5, Journal of Bacteriology, 2014, 196 (17): 3122 – 3133.
(10)Harry W. Duckworth, Nham T. Nguyen, Yin Gao, Lynda J. Donald, Robert Maurus, Ayead Ayed, Brigitte Bruneau, Gary D. Brayer, Enzyme-substrate complexes of allosteric citrate synthase: evidence for a novel intermediate in substrate binding, Biochimica et Biophysica Acta, 2013, 1834(12): 2546 – 2553.
着作教材: (1)Yin Gao, Anna Vinnikova, Inka Brockhausen, Functional identification of bacterial glucosyltransferase WbdN, Methods. Mol. Biol., 2013, 1022: 199 – 214, Springer Science+Business Media New York, 2013
(2)Inka Brockhausen, Yin Gao, Chapter 8. Structural glycobiology: applications in cancer research, CRC Press, Taylor & Francis Group (Print ISBN: 978-1-4398-5460-0), 2012

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